After years of effort, two research teams have developed ‘laser phase plate’ systems that could help cryo-electron-microscopy users to generate high-quality structures for a broad range of proteins. For 15 years, structural biologists have debated the feasibility of a technology that could improve the resolution of protein structures produced by cryo-electron microscopy (cryo-EM). The technology, called a laser phase plate (LPP), should extend t... [2796 chars]
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