Scientists discover bacteria can “explode” to spread antibiotic resistance

Scientists have uncovered a surprising twist in how bacteria share genes—including those that spread antibiotic resistance. Tiny virus-like particles called gene transfer agents (GTAs), once ancient viral invaders, have been repurposed by bacteria into delivery systems that shuttle DNA between neighboring cells. The study reveals a key control hub of three genes, dubbed LypABC, that triggers bacterial cells to burst open and release these DNA-packed couriers. GTAs resemble bacteriophages (viruses that infect bacteria), but they are no longer harmful invaders. Instead, they are derived from ancient viruses that bacteria have adapted and brought under their own control. Virus-Like Particles Deliver DNA Betw... [5782 chars]