A roadmap for safer, explainable protein-design AI

Protein language models are accelerating biotech but largely operate as black boxes. In Nature Machine Intelligence, researchers at the Centre for Genomic Regulation (CRG) publish the most comprehensive review yet of explainable AI in protein design, with a roadmap for making these powerful tools transparent, trustworthy and safe to deploy. Protein language models are artificial intelligence tools which help engineer proteins with useful properties, including completely new structures never seen before in nature. The technology has huge potential for addressing global challenges, such a... [7224 chars]