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First β-Arrestin Inhibitors Could Transform Drug Design

Three drug-like molecules selectively inhibit β-arrestins, providing new tools to study cell signaling and develop more precise medicines. To function normally, nearly every cell in the human body relies on G-protein coupled receptors (GPCRs) to receive and send signals. That’s why GPCRs are targeted by roughly one-third of all FDA‑approved drugs. But the signals from these receptors do... [3963 chars]

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