Gut microbiome-derived metabolites may influence stress-related mental disorders through neural, immune, endocrine, and epigenetic pathways. Evidence is strongest for depression and preclinical models, while larger longitudinal human studies are needed to establish causality and clinical value. From short-chain fatty acids to bile acids, researchers trace how microbial chemistry could influence brain signaling and point to potential adjunctive treatments that still require stronger human evidence. Study: Gut microbiota-driven metabolites mo... [7008 chars]
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